僅用于工業(yè)應用或科學研究，不可用于人類或動物的臨床診斷或治療，非藥用.Zalcitabine （trade name Hivid） is a nucleoside analog HIV reverse transcriptase inhibitor （NARTI）. It is an antiviral pyrimidine nucleoside analogue effective against HIV replication. 2′,3′-Dideoxycytidine, when activated to its triphosphate, is incorporated into DNA by HIV-1 RT （HIV-1 reverse transcriptase）, causing DNA chain termination and viral replication. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration （FDA） for the treatment of HIV/AIDS. It is used as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events.
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